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Chengdu Henghui Pharmaceutical Co., Ltd.(expird)

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Chengdu Henghui Pharmaceutical Co., Ltd.(expird)

Business Type:Lab/Research institutions

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Year Established:
2017

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Chengdu Henghui Pharmaceutical Co., Ltd.(expird)

Country: China (Mainland)

Business Type:Lab/Research institutions

Vipadenant high quality

CAS NO.442908-10-3

  • Min.Order: 10 Milligram
  • Payment Terms:
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Product Details

Keywords

  • Vipadenant
  • BIIB-014
  • Vipadenant Chengdu Hneghui Pharm Tec Co. LTD

Quick Details

  • ProName: Vipadenant high quality
  • CasNo: 442908-10-3
  • Molecular Formula: C16H15N7O
  • Appearance: off-white powder
  • Application: For laboratory use only- not intended ...
  • DeliveryTime: 3 days
  • PackAge: Aluminum foil bag
  • ProductionCapacity: 10 Kilogram/Month
  • Purity: ≥98%
  • Storage: room temperature
  • Transportation: by air
  • LimitNum: 10 Milligram

Superiority

We are a CRO company, and our Research and Development team is consisted of PhDs and Masters in chemistry and pharmacy.

We are committed to protect our customer’s privacy with the highest level of ethical standard. Our dedicated team will follow up on every order and provide instant feedback on the status to our customer.

We stand behind our product by providing a complete QA report. The test data of customer order can be provided upon request.

We make our efforts to offer customer innovative, customized, high-quality service.

Our custom manufacturing encompasses everything from pharmaceutical intermediates to API.

 

 

 

Details

Vipadenant is an adenosine receptor antagonist, with Ki of 1.3 nM and 68 nM for A2A and A1, respectively. IC50 & Target: Ki: 1.3 nM (A2A), 68 nM (A1), 1005 nM (A3) In Vivo: Vipadenant (0.3-30 mg/kg) produces a dose-dependent reduction in catalepsy. Vipadenant (10 mg/kg) does not produce any statistically significant dyskinetic episodes in 6-OHDA-lesioned rats during a 19-day dosing regimen[1]. In the mouse and rat haloperidol-induced hypolocomotion models, vipadenant has a minimum effective dose of 0.1 and 1 mg/kg, respectively. Vipadenant (3 and 10 mg/kg, p.o.) is able to increase contralateral rotations in 6-OHDA lesioned rats

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