Keywords

• RAF 709
• RAF709
• MW: 542.55

Quick Details

• ProName: RAF-709
• CasNo: 1628838-42-5
• Appearance: white solid powder
• Application: The compound could only be used for ex...
• Port: shanghai
• ProductionCapacity: 100 Gram/Month
• Purity: 99%
• Storage: -20 degrees for 3 years.
• LimitNum: 100 Metric Ton

Superiority

We are a CRO company, and our Research and Development team is consisted of PhDs and Masters in chemistry and pharmacy.

We are committed to protect our customer’s privacy with the highest level of ethical standard. Our dedicated team will follow up on every order and provide instant feedback on the status to our customer.

We stand behind our product by providing a complete QA report. The test data of customer order can be provided upon request.

We make our efforts to offer customer innovative, customized, high-quality service.

Our custom manufacturing encompasses everything from pharmaceutical intermediates to API.

Details

RAF709 is a novel Raf kinase inhibitor extracted from patent WO2014151616A1, compound example 131, has an IC₅₀ of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively.
IC50 & Target: 0.5 nM (c-Raf), 1.8 nM (b-Raf)
InVitro: The invention provides compounds (e.g., RAF709) that inhibit Raf kinases, and are accordingly useful for treating certain disorders associated with excessive Raf kinase activity, including cell proliferation disorders such as cancers