Business Type:Lab/Research institutions
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Country: China (Mainland)
Business Type:Lab/Research institutions
CP21R7 is a potent and selective GSK-3β inhibitor. CP21R7 can inhibitor enhances the induction of KDR+precursors prior to vascular commitment.Cp21R7 compound induced the highest luciferase activity at a concentration of 3 μ M.Immunofluorescence staining revealed that CP21 significantly increased total levels of intracellular -catenin. Activation of WNT signaling via GSK3 inhibition with CP21 induced commitment of hPSCs towards mesoderm.