Vipadenant high quality CAS NO.442908-10-3

Min.Order: 10 Milligram
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Vipadenant
BIIB-014
Vipadenant Chengdu Hneghui Pharm Tec Co. LTD

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ProName: Vipadenant high quality
CasNo: 442908-10-3
Molecular Formula: C16H15N7O
Appearance: off-white powder
Application: For laboratory use only- not intended ...
DeliveryTime: 3 days
PackAge: Aluminum foil bag
ProductionCapacity: 10 Kilogram/Month
Purity: ≥98%
Storage: room temperature
Transportation: by air
LimitNum: 10 Milligram

Superiority

We are a CRO company, and our Research and Development team is consisted of PhDs and Masters in chemistry and pharmacy.

We are committed to protect our customer’s privacy with the highest level of ethical standard. Our dedicated team will follow up on every order and provide instant feedback on the status to our customer.

We stand behind our product by providing a complete QA report. The test data of customer order can be provided upon request.

We make our efforts to offer customer innovative, customized, high-quality service.

Our custom manufacturing encompasses everything from pharmaceutical intermediates to API.

Details

Vipadenant is an adenosine receptor antagonist, with K_i of 1.3 nM and 68 nM for A_2A and A₁, respectively. IC50 & Target: Ki: 1.3 nM (A_2A), 68 nM (A₁), 1005 nM (A₃) In Vivo: Vipadenant (0.3-30 mg/kg) produces a dose-dependent reduction in catalepsy. Vipadenant (10 mg/kg) does not produce any statistically significant dyskinetic episodes in 6-OHDA-lesioned rats during a 19-day dosing regimen^[1]. In the mouse and rat haloperidol-induced hypolocomotion models, vipadenant has a minimum effective dose of 0.1 and 1 mg/kg, respectively. Vipadenant (3 and 10 mg/kg, p.o.) is able to increase contralateral rotations in 6-OHDA lesioned rats

Vipadenant high quality CAS NO.442908-10-3

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