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Chengdu Henghui Pharmaceutical Co., Ltd.(expird)

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Chengdu Henghui Pharmaceutical Co., Ltd.(expird)

Business Type:Lab/Research institutions

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Year Established:
2017
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Chengdu Henghui Pharmaceutical Co., Ltd.(expird)

Country: China (Mainland)

Business Type:Lab/Research institutions

XMD8-87

CAS NO.1234480-46-6

  • Min.Order: 1 Gram
  • Payment Terms:
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Product Details

Keywords

  • XMD8-87
  • ACK1-B19
  • best price and high purity

Quick Details

  • ProName: XMD8-87
  • CasNo: 1234480-46-6
  • Molecular Formula: C24H27N7O2
  • Appearance: off-white powder
  • Application: For laboratory use only- not intended ...
  • ProductionCapacity: 1 Kilogram/Quarter
  • Purity: ≥98%
  • Storage: room temperature
  • Transportation: by air
  • LimitNum: 1 Gram

Superiority

We are a CRO company, and our Research and Development team is consisted of PhDs and Masters in chemistry and pharmacy.

We are committed to protect our customer’s privacy with the highest level of ethical standard. Our dedicated team will follow up on every order and provide instant feedback on the status to our customer.

We stand behind our product by providing a complete QA report. The test data of customer order can be provided upon request.

We make our efforts to offer customer innovative, customized, high-quality service.

Our custom manufacturing encompasses everything from pharmaceutical intermediates to API.

 

 

 

Details

XMD8-87 is a potent TNK2 inhibitor with IC50 values of 38 and 113 nM for the D163E and R806Q mutations, respectively. IC50 & Target: IC50: 38 nM (TNK2, D163E mutation), 113 nM (TNK2, R806Q mutation). In Vitro: XMD8-87 potently inhibits the growth of the TNK2 mutant expressing cell lines while having little or no effect on the control cells out to the highest tested concentrations (1,000 nM). XMD8-87 has IC50s of 38 nM and 113 nM for the D163E and R806Q mutations. The effects of XMD8-87 on TNK2 cell lines are largely due to on-target effects on TNK2. Auto-phosphorylation of overexpressed TNK2 mutants could be blocked with TNK2 inhibitor XMD8-87

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